Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro.

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Title: Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro.
Authors: Hameedi MA; SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Structural Molecular Biology, Menlo Park, CA, 94025, USA.; SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Biosciences, Menlo Park, CA, 94025, USA.; Department of Structural Biology, Stanford University, Stanford, CA, 94305, USA.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA., T Prates E; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Garvin MR; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Mathews II; SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Structural Molecular Biology, Menlo Park, CA, 94025, USA., Amos BK; Department of Horticulture, University of Kentucky, Lexington, KY, USA., Demerdash O; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Bechthold M; Department of Structural Biology, Stanford University, Stanford, CA, 94305, USA., Iyer M; Chapman University School of Pharmacy, Irvine, CA, 92618, USA., Rahighi S; Chapman University School of Pharmacy, Irvine, CA, 92618, USA., Kneller DW; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Kovalevsky A; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Irle S; Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA., Vuong VQ; The Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee Knoxville, Knoxville, TN, USA., Mitchell JC; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Labbe A; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA., Galanie S; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ, 07065, USA., Wakatsuki S; SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Structural Molecular Biology, Menlo Park, CA, 94025, USA. soichi.wakatsuki@stanford.edu.; SLAC National Accelerator Laboratory, Stanford Synchrotron Radiation Lightsource, Biosciences, Menlo Park, CA, 94025, USA. soichi.wakatsuki@stanford.edu.; Department of Structural Biology, Stanford University, Stanford, CA, 94305, USA. soichi.wakatsuki@stanford.edu.; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA. soichi.wakatsuki@stanford.edu., Jacobson D; National Virtual Biotechnology Laboratory, US Department of Energy, Washington, DC, USA. jacobsonda@ornl.gov.; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA. jacobsonda@ornl.gov.
Source: Nature communications [Nat Commun] 2022 Sep 08; Vol. 13 (1), pp. 5285. Date of Electronic Publication: 2022 Sep 08.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-022-32922-9