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The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition.

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Title: The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition.
Authors: Motozono C; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan. motozono@kumamoto-u.ac.jp.; Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, 5650871, Japan. motozono@kumamoto-u.ac.jp., Toyoda M; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan., Tan TS; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan., Hamana H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, 9300194, Japan., Goto Y; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan.; Department of Respiratory Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan., Aritsu Y; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Osaka, 577-8502, Japan., Miyashita Y; Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan.; Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 8608556, Japan., Oshiumi H; Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan., Nakamura K; Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 8608556, Japan., Okada S; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan., Udaka K; Department of Immunology, Kochi University, Kochi, 783-8505, Japan., Kitamatsu M; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Osaka, 577-8502, Japan., Kishi H; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, 9300194, Japan., Ueno T; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan. uenotaka@kumamoto-u.ac.jp.
Source: Nature communications [Nat Commun] 2022 Sep 21; Vol. 13 (1), pp. 5440. Date of Electronic Publication: 2022 Sep 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition.
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  Data: <searchLink fieldCode="AU" term="%22Motozono+C%22">Motozono C</searchLink>; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan. motozono@kumamoto-u.ac.jp.; Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, 5650871, Japan. motozono@kumamoto-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Toyoda+M%22">Toyoda M</searchLink>; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan.<br /><searchLink fieldCode="AU" term="%22Tan+TS%22">Tan TS</searchLink>; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan.<br /><searchLink fieldCode="AU" term="%22Hamana+H%22">Hamana H</searchLink>; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, 9300194, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+Y%22">Goto Y</searchLink>; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan.; Department of Respiratory Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan.<br /><searchLink fieldCode="AU" term="%22Aritsu+Y%22">Aritsu Y</searchLink>; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Miyashita+Y%22">Miyashita Y</searchLink>; Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan.; Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 8608556, Japan.<br /><searchLink fieldCode="AU" term="%22Oshiumi+H%22">Oshiumi H</searchLink>; Department of Immunology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, 8608556, Japan.<br /><searchLink fieldCode="AU" term="%22Nakamura+K%22">Nakamura K</searchLink>; Department of Pediatrics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 8608556, Japan.<br /><searchLink fieldCode="AU" term="%22Okada+S%22">Okada S</searchLink>; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan.<br /><searchLink fieldCode="AU" term="%22Udaka+K%22">Udaka K</searchLink>; Department of Immunology, Kochi University, Kochi, 783-8505, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamatsu+M%22">Kitamatsu M</searchLink>; Department of Applied Chemistry, Faculty of Science and Engineering, Kindai University, Osaka, 577-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Kishi+H%22">Kishi H</searchLink>; Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, 9300194, Japan.<br /><searchLink fieldCode="AU" term="%22Ueno+T%22">Ueno T</searchLink>; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, 8600811, Japan. uenotaka@kumamoto-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Sep 21; Vol. 13 (1), pp. 5440. <i>Date of Electronic Publication: </i>2022 Sep 21.
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