Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.
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| Title: | Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors. |
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| Authors: | Kobayashi Y; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, 1040045, Japan., Oxnard GR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Cohen EF; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Mahadevan NR; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Hung YP; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA., Bertram AA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Heppner DE; Department of Chemistry, University at Buffalo, State University of New York, Buffalo, NY, 14260-3000, USA.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Ribeiro MF; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Sacardo KP; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Saddi R; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Macedo MP; Department of Pathology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Blasco RB; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA., Li J; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA., Kurppa KJ; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, Turku, 20520, Finland., Nguyen T; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Voligny E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Ananda G; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Chiarle R; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, 10126, Italy., Katz A; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu. |
| Source: | Nature communications [Nat Commun] 2022 Sep 24; Vol. 13 (1), pp. 5614. Date of Electronic Publication: 2022 Sep 24. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-33210-2 |
