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Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.

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Title: Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.
Authors: Kobayashi Y; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, 1040045, Japan., Oxnard GR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Cohen EF; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Mahadevan NR; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Hung YP; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA., Bertram AA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Heppner DE; Department of Chemistry, University at Buffalo, State University of New York, Buffalo, NY, 14260-3000, USA.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA., Ribeiro MF; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Sacardo KP; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Saddi R; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Macedo MP; Department of Pathology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Blasco RB; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA., Li J; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA., Kurppa KJ; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, Turku, 20520, Finland., Nguyen T; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Voligny E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Ananda G; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Chiarle R; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, 10126, Italy., Katz A; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.
Source: Nature communications [Nat Commun] 2022 Sep 24; Vol. 13 (1), pp. 5614. Date of Electronic Publication: 2022 Sep 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kobayashi+Y%22">Kobayashi Y</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, 1040045, Japan.<br /><searchLink fieldCode="AU" term="%22Oxnard+GR%22">Oxnard GR</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+EF%22">Cohen EF</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Mahadevan+NR%22">Mahadevan NR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Alessi+JV%22">Alessi JV</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Hung+YP%22">Hung YP</searchLink>; Department of Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA.<br /><searchLink fieldCode="AU" term="%22Bertram+AA%22">Bertram AA</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Heppner+DE%22">Heppner DE</searchLink>; Department of Chemistry, University at Buffalo, State University of New York, Buffalo, NY, 14260-3000, USA.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.<br /><searchLink fieldCode="AU" term="%22Ribeiro+MF%22">Ribeiro MF</searchLink>; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil.<br /><searchLink fieldCode="AU" term="%22Sacardo+KP%22">Sacardo KP</searchLink>; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil.<br /><searchLink fieldCode="AU" term="%22Saddi+R%22">Saddi R</searchLink>; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil.<br /><searchLink fieldCode="AU" term="%22Macedo+MP%22">Macedo MP</searchLink>; Department of Pathology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil.<br /><searchLink fieldCode="AU" term="%22Blasco+RB%22">Blasco RB</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Kurppa+KJ%22">Kurppa KJ</searchLink>; Institute of Biomedicine, and MediCity Research Laboratories, University of Turku, Turku, 20520, Finland.<br /><searchLink fieldCode="AU" term="%22Nguyen+T%22">Nguyen T</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Voligny+E%22">Voligny E</searchLink>; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Ananda+G%22">Ananda G</searchLink>; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Chiarle+R%22">Chiarle R</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, 10126, Italy.<br /><searchLink fieldCode="AU" term="%22Katz+A%22">Katz A</searchLink>; Department of Medical Oncology, Hospital Sírio-Libanês, São Paulo-SP, 01308-050, Brazil.<br /><searchLink fieldCode="AU" term="%22Tolstorukov+MY%22">Tolstorukov MY</searchLink>; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Sholl+LM%22">Sholl LM</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Jänne+PA%22">Jänne PA</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. pasi_janne@dfci.harvard.edu.
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