Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection.

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Title: Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection.
Authors: Quintana JF; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK. juan.quintana@glasgow.ac.uk.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK. juan.quintana@glasgow.ac.uk., Chandrasegaran P; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK., Sinton MC; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK., Briggs EM; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK., Otto TD; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Infection and Immunity, MVLS, University of Glasgow, Glasgow, UK., Heslop R; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK., Bentley-Abbot C; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK., Loney C; School of Infection and Immunity, MVLS, University of Glasgow, Glasgow, UK.; MRC Centre for Virus Research, University of Glasgow, Glasgow, UK., de Lecea L; Stanford University School of Medicine, Stanford, CA, USA., Mabbott NA; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK., MacLeod A; Wellcome Centre for Integrative Parasitology (WCIP), University of Glasgow, Glasgow, UK.; School of Biodiversity, One Health, and Veterinary Medicine (SBOHVM), MVLS, University of Glasgow, Glasgow, UK.
Source: Nature communications [Nat Commun] 2022 Sep 30; Vol. 13 (1), pp. 5752. Date of Electronic Publication: 2022 Sep 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-33542-z