Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.
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| Title: | Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis. |
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| Authors: | Han Z; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China.; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Liu M; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Xie Y; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Zeng K; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Zhan Z; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Chen Y; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Wang L; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Chen X; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Luo Y; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Zeng Y; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Zhan H; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China., Lin Y; Department of Gastroenterology, Yangjiang People's Hospital, Yangjiang, 529599, China., Zhang K; Department of Oncology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, 510999, China., Zhu X; Department of Radiation Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510285, China., Liu S; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Luo X; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. luoxiaobei63@126.com., Zhou A; Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China. aidern0927@smu.edu.cn.; Department of Radiation Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510285, China. aidern0927@smu.edu.cn.; Guangdong Province Key Laboratory of Molecular Tumor Pathology, School of Basic Medical Science, Southern Medical University, Guangzhou, 510515, China. aidern0927@smu.edu.cn. |
| Source: | Cell death discovery [Cell Death Discov] 2022 Nov 04; Vol. 8 (1), pp. 445. Date of Electronic Publication: 2022 Nov 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-022-01241-9 |
