Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study.
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| Title: | Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study. |
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| Authors: | Stieh DJ; Janssen Vaccines and Prevention Leiden, the Netherlands., Barouch DH; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Comeaux C; Janssen Vaccines and Prevention Leiden, the Netherlands., Sarnecki M; Janssen Vaccines, Bern, Switzerland., Stephenson KE; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Walsh SR; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sawant S; Department of Surgery, Center for Human Systems Immunology, and Duke Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Heptinstall J; Department of Surgery, Center for Human Systems Immunology, and Duke Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Tomaras GD; Department of Surgery, Center for Human Systems Immunology, and Duke Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Kublin JG; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Cohen KW; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., De Rosa SC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Ferrari G; Department of Surgery, Center for Human Systems Immunology, and Duke Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Montefiori D; Department of Surgery, Center for Human Systems Immunology, and Duke Human Vaccine Institute, Duke University, Durham, North Carolina, USA., Mann P; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Nijs S; Janssen Research and Development, Beerse, Belgium., Callewaert K; Janssen Research and Development, Beerse, Belgium., Goepfert PA; Division of Infectious Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Edupuganti S; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Karita E; Rwanda Zambia HIV Research Group, Kigali, Rwanda., Seaman MS; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Baden LR; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Pau MG; Janssen Vaccines and Prevention Leiden, the Netherlands., Schuitemaker H; Janssen Vaccines and Prevention Leiden, the Netherlands., Tomaka F; Janssen Research and Development, Titusville, New Jersey, USA. |
| Corporate Authors: | ASCENT/HVTN118/HPX2003 Study Team |
| Source: | The Journal of infectious diseases [J Infect Dis] 2023 Apr 18; Vol. 227 (8), pp. 939-950. |
| Publication Type: | Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1537-6613 |
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| DOI: | 10.1093/infdis/jiac445 |
