Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.

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Title: Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.
Authors: Cordes M; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands., Canté-Barrett K; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands., van den Akker EB; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands.; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Moretti FA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Kiełbasa SM; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands., Vloemans SA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Garcia-Perez L; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Teodosio C; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain., van Dongen JJM; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain., Pike-Overzet K; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Reinders MJT; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands., Staal FJT; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands.; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
Source: Science immunology [Sci Immunol] 2022 Nov 18; Vol. 7 (77), pp. eade0182. Date of Electronic Publication: 2022 Nov 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2470-9468
DOI:10.1126/sciimmunol.ade0182