Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.

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Title: Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.
Authors: Cordes M; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands., Canté-Barrett K; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands., van den Akker EB; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands.; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Moretti FA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Kiełbasa SM; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands., Vloemans SA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Garcia-Perez L; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Teodosio C; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain., van Dongen JJM; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain., Pike-Overzet K; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Reinders MJT; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands., Staal FJT; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands.; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
Source: Science immunology [Sci Immunol] 2022 Nov 18; Vol. 7 (77), pp. eade0182. Date of Electronic Publication: 2022 Nov 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
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  Data: Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus.
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  Data: <searchLink fieldCode="AU" term="%22Cordes+M%22">Cordes M</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Canté-Barrett+K%22">Canté-Barrett K</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Akker+EB%22">van den Akker EB</searchLink>; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands.; Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Moretti+FA%22">Moretti FA</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kiełbasa+SM%22">Kiełbasa SM</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vloemans+SA%22">Vloemans SA</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Garcia-Perez+L%22">Garcia-Perez L</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Teodosio+C%22">Teodosio C</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22van+Dongen+JJM%22">van Dongen JJM</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Centro de Investigación del Cáncer-Instituto de Biología Molecular y Celular del Cáncer (CIC-IBMCC, USAL-CSIC-FICUS), Department of Medicine, University of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Pike-Overzet+K%22">Pike-Overzet K</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Reinders+MJT%22">Reinders MJT</searchLink>; Leiden Computational Biology Center, Leiden University Medical Center, Leiden, Netherlands.; Delft Bioinformatics Lab, Delft University of Technology, Delft, Netherlands.<br /><searchLink fieldCode="AU" term="%22Staal+FJT%22">Staal FJT</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden University Medical Center, Netherlands.; Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2022 Nov 18; Vol. 7 (77), pp. eade0182. <i>Date of Electronic Publication: </i>2022 Nov 11.
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