Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria.
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| Title: | Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria. |
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| Authors: | Gansane A; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 220801 BP 2208, Ouagadougou, Burkina Faso. agansane.cnrfp@fasonet.bf., Lingani M; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Ouagadougou, Burkina Faso., Yeka A; Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda., Nahum A; Centre de Recherches Entomologique de Cotonou (CREC), Cotonou, Benin., Bouyou-Akotet M; Département de Parasitologie-Mycologie-Médecine Tropicale, Faculté de Médecine - Université des Sciences de la Santé, Libreville, Gabon., Mombo-Ngoma G; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany., Kaguthi G; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya., Barceló C; Medicines for Malaria Venture, Geneva, Switzerland., Laurijssens B; BEL Pharm Consulting, Chambonas, France., Cantalloube C; Sanofi Research and Development, Chilly Mazarin, France., Macintyre F; Medicines for Malaria Venture, Geneva, Switzerland., Djeriou E; Sanofi Research and Development, Chilly Mazarin, France., Jessel A; Sanofi Research and Development, Bridgewater, NJ, USA., Bejuit R; Sanofi Research and Development, Chilly Mazarin, France., Demarest H; Medicines for Malaria Venture, Geneva, Switzerland., Marrast AC; Medicines for Malaria Venture, Geneva, Switzerland., Debe S; Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 220801 BP 2208, Ouagadougou, Burkina Faso., Tinto H; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Ouagadougou, Burkina Faso., Kibuuka A; Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda., Nahum D; Centre de Recherches Entomologique de Cotonou (CREC), Cotonou, Benin., Mawili-Mboumba DP; Département de Parasitologie-Mycologie-Médecine Tropicale, Faculté de Médecine - Université des Sciences de la Santé, Libreville, Gabon., Zoleko-Manego R; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany., Mugenya I; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya., Olewe F; Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya.; Centre for Research in Therapeutic Sciences (CREATES), Strathmore University, Nairobi, Kenya., Duparc S; Medicines for Malaria Venture, Geneva, Switzerland., Ogutu B; Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya.; Centre for Research in Therapeutic Sciences (CREATES), Strathmore University, Nairobi, Kenya. |
| Source: | Malaria journal [Malar J] 2023 Jan 03; Vol. 22 (1), pp. 2. Date of Electronic Publication: 2023 Jan 03. |
| Publication Type: | Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1475-2875 |
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| DOI: | 10.1186/s12936-022-04420-2 |
