Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma.
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| Title: | Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. |
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| Authors: | Alejo S; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Palacios BE; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Venkata PP; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., He Y; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Li W; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Johnson JD; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Chen Y; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China.; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Jayamohan S; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Pratap UP; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Clarke K; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Zou Y; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Lv Y; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Weldon K; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Viswanadhapalli S; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Lai Z; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Molecular Medicine, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Ye Z; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Chen Y; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China.; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Gilbert AR; Department of Pathology and Laboratory Medicine, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Suzuki T; The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan., Tekmal RR; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Zhao W; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Zheng S; Greehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Vadlamudi RK; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Audie L. Murphy South Texas Veterans Health Care System, San Antonio, Texas, 78229, USA., Brenner AJ; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Department of Hematology & Oncology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA., Sareddy GR; Department of Obstetrics and Gynecology, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, Texas, 78229, USA. |
| Source: | Neuro-oncology [Neuro Oncol] 2023 Jul 06; Vol. 25 (7), pp. 1249-1261. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1523-5866 |
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| DOI: | 10.1093/neuonc/noad018 |
