Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.

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Title: Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.
Authors: Fujiwara Y; Department of Thoracic Oncology, Aichi Cancer Center, Nagoya, Japan.; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan., Makihara R; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan., Hase T; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan., Hashimoto N; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan., Naito T; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan., Tsubata Y; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan., Okuno T; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan., Takahashi T; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Kobayashi H; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Shinno Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Zenke Y; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan., Ikeda T; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan., Hosomi Y; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan., Watanabe K; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan., Kitazono S; Department of Thoracic Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Sakiyama N; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan., Makino Y; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.; Departments of Pharmacy and Cancer Genome Medicine, Saitama Medical University International Medical Center, Saitama, Japan., Yamamoto N; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.; Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Source: Cancer science [Cancer Sci] 2023 May; Vol. 114 (5), pp. 2087-2097. Date of Electronic Publication: 2023 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1349-7006
DOI:10.1111/cas.15736