Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.

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Title: Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.
Authors: Fujiwara Y; Department of Thoracic Oncology, Aichi Cancer Center, Nagoya, Japan.; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan., Makihara R; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan., Hase T; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan., Hashimoto N; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan., Naito T; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan., Tsubata Y; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan., Okuno T; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan., Takahashi T; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Kobayashi H; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Shinno Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Zenke Y; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan., Ikeda T; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan., Hosomi Y; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan., Watanabe K; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan., Kitazono S; Department of Thoracic Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Sakiyama N; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan., Makino Y; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.; Departments of Pharmacy and Cancer Genome Medicine, Saitama Medical University International Medical Center, Saitama, Japan., Yamamoto N; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.; Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Source: Cancer science [Cancer Sci] 2023 May; Vol. 114 (5), pp. 2087-2097. Date of Electronic Publication: 2023 Feb 14.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE
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  Data: Pharmacokinetic and dose-finding study of osimertinib in patients with impaired renal function and low body weight.
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  Data: <searchLink fieldCode="AU" term="%22Fujiwara+Y%22">Fujiwara Y</searchLink>; Department of Thoracic Oncology, Aichi Cancer Center, Nagoya, Japan.; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Makihara+R%22">Makihara R</searchLink>; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hase+T%22">Hase T</searchLink>; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Hashimoto+N%22">Hashimoto N</searchLink>; Department of Respiratory Medicine, Graduate School of Medicine, Nagoya University, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Naito+T%22">Naito T</searchLink>; Department of Respiratory Medicine, Mitsui Memorial Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tsubata+Y%22">Tsubata Y</searchLink>; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan.<br /><searchLink fieldCode="AU" term="%22Okuno+T%22">Okuno T</searchLink>; Division of Medical Oncology and Respiratory Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+T%22">Takahashi T</searchLink>; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+H%22">Kobayashi H</searchLink>; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Shinno+Y%22">Shinno Y</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Zenke+Y%22">Zenke Y</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeda+T%22">Ikeda T</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Hosomi+Y%22">Hosomi Y</searchLink>; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+K%22">Watanabe K</searchLink>; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kitazono+S%22">Kitazono S</searchLink>; Department of Thoracic Medical Oncology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sakiyama+N%22">Sakiyama N</searchLink>; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Makino+Y%22">Makino Y</searchLink>; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.; Departments of Pharmacy and Cancer Genome Medicine, Saitama Medical University International Medical Center, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+N%22">Yamamoto N</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.; Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101168776%22">Cancer science</searchLink> [Cancer Sci] 2023 May; Vol. 114 (5), pp. 2087-2097. <i>Date of Electronic Publication: </i>2023 Feb 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+Publishing+on+behalf+of+the+Japanese+Cancer+Association%22">Wiley Publishing on behalf of the Japanese Cancer Association </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101168776 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1349-7006 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213479032%22">13479032 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Sci <i>Subsets: </i>MEDLINE
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