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Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators.

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Title: Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators.
Authors: Tang S; Division of Pharmacy and Optometry, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PL, UK., Garzon Sanz M; Division of Pharmacy and Optometry, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PL, UK., Smith O; Division of Pharmacy and Optometry, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PL, UK., Krämer A; Structural Genomics Consortium (SGC), 60438 Frankfurt Am Main, Germany.; Buchmann Institute for Life Sciences (BMLS), 60438 Frankfurt Am Main, Germany.; Institut für Pharmazeutische Chemie, Goethe University, 60438 Frankfurt Am Main, Germany.; Frankfurt Cancer Institute (FCI), 60596 Frankfurt Am Main, Germany., Egbase D; Department of Diabetes, School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Sciences & Medicine, King's College London, London SE1 1UL, UK., Caton PW; Department of Diabetes, School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Sciences & Medicine, King's College London, London SE1 1UL, UK., Knapp S; Structural Genomics Consortium (SGC), 60438 Frankfurt Am Main, Germany.; Buchmann Institute for Life Sciences (BMLS), 60438 Frankfurt Am Main, Germany.; Institut für Pharmazeutische Chemie, Goethe University, 60438 Frankfurt Am Main, Germany.; Frankfurt Cancer Institute (FCI), 60596 Frankfurt Am Main, Germany., Butterworth S; Division of Pharmacy and Optometry, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester M13 9PL, UK.
Source: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2023 Feb; Vol. 13 (2), pp. 709-721. Date of Electronic Publication: 2022 Aug 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-3835
DOI:10.1016/j.apsb.2022.07.016