Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.

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Title: Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.
Authors: Simigdala N; Biomedical Research Foundation Academy of Athens, Athens, Greece. nsimigdala@bioacademy.gr., Chalari A; Biomedical Research Foundation Academy of Athens, Athens, Greece., Sklirou AD; Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece., Chavdoula E; Biomedical Research Foundation Academy of Athens, Athens, Greece.; Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.; The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH, USA., Papafotiou G; Biomedical Research Foundation Academy of Athens, Athens, Greece., Melissa P; Biomedical Research Foundation Academy of Athens, Athens, Greece., Kafalidou A; Biomedical Research Foundation Academy of Athens, Athens, Greece., Paschalidis N; Biomedical Research Foundation Academy of Athens, Athens, Greece., Pateras IS; 2nd Department of Pathology, Medical School, 'Attikon' University Hospital, National and Kapodistrian University of Athens, Athens, Greece., Athanasiadis E; Biomedical Research Foundation Academy of Athens, Athens, Greece., Konstantopoulos D; Institute for Fundamental Biomedical Research, BSRC 'Alexander Fleming', 16672, Vari, Greece., Trougakos IP; Department of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece., Klinakis A; Biomedical Research Foundation Academy of Athens, Athens, Greece. aklinakis@bioacademy.gr.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 Mar 18; Vol. 80 (4), pp. 100. Date of Electronic Publication: 2023 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-023-04734-7