Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential.
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| Title: | Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential. |
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| Authors: | Harrington S; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada.; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Pyche J; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada.; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada., Burns AR; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Spalholz T; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318, Leipzig, Germany., Ryan KT; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA., Baker RJ; The Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Ching J; The Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Rufener L; INVENesis Sàrl, Route de Neuchâtel 15A, 2072, St Blaise (NE), Switzerland., Lautens M; The Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Kulke D; Research Parasiticides, Bayer Animal Health GmbH, Monheim, Germany.; Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, USA.; Global Innovation, Boehringer Ingelheim Vetmedica GmbH, Binger Str. 173, 55218, Ingelheim am Rhein, Germany., Vernudachi A; INVENesis France Sàrl, 147 Avenue André Maginot, Tours, 37100, France., Zamanian M; Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA., Deuther-Conrad W; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318, Leipzig, Germany., Brust P; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 04318, Leipzig, Germany.; The Lübeck Institute of Experimental Dermatology, University Medical Center Schleswig-Holstein, 23562, Lübeck, Germany., Roy PJ; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada. peter.roy@utoronto.ca.; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, M5S 3E1, Canada. peter.roy@utoronto.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada. peter.roy@utoronto.ca. |
| Source: | Nature communications [Nat Commun] 2023 Mar 31; Vol. 14 (1), pp. 1816. Date of Electronic Publication: 2023 Mar 31. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-37452-6 |
