Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided by design of experiments.
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| Title: | Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided by design of experiments. |
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| Authors: | Schwarz H; Cell Technology Group, Department of Industrial Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.; AdBIOPRO, Competence Centre for Advanced BioProduction by Continuous Processing, Stockholm, Sweden., Lee K; MilliporeSigma, Stoneham, MA, USA., Castan A; Cytiva, Uppsala, Sweden., Chotteau V; Cell Technology Group, Department of Industrial Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.; AdBIOPRO, Competence Centre for Advanced BioProduction by Continuous Processing, Stockholm, Sweden. |
| Source: | Biotechnology and bioengineering [Biotechnol Bioeng] 2023 Sep; Vol. 120 (9), pp. 2523-2541. Date of Electronic Publication: 2023 Apr 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0290 |
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| DOI: | 10.1002/bit.28397 |