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Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.

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Bibliographic Details
Title: Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
Authors: Crawford JJ; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address: crawford.james@gene.com., Feng J; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Brightbill HD; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Johnson AR; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Wright M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Kolesnikov A; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Lee W; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Castanedo GM; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Do S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Blaquiere N; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Staben ST; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Chiang PC; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Fan PW; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Baumgardner M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Wong S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Godemann R; Evotec SE., Manfred Eigen Campus, Essener Bogen 7, Hamburg 22419, Germany., Grabbe A; Evotec SE., Manfred Eigen Campus, Essener Bogen 7, Hamburg 22419, Germany., Wiegel C; Evotec SE., Manfred Eigen Campus, Essener Bogen 7, Hamburg 22419, Germany., Sujatha-Bhaskar S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Hymowitz SG; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Liau N; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Hsu PL; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., McEwan PA; Evotec SE., Manfred Eigen Campus, Essener Bogen 7, Hamburg 22419, Germany., Ismaili MHA; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Landry ML; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 01; Vol. 89, pp. 129277. Date of Electronic Publication: 2023 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3405
DOI:10.1016/j.bmcl.2023.129277