High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner.

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Title: High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner.
Authors: Assini JM; Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5B7, Canada; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada., Clark JR; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada; Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5B7, Canada., Youssef A; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada., Xing C; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada., Doerfler AM; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA., Park SH; Department of Bioengineering, Rice University, Houston, USA., Saxena L; Department of Bioengineering, Rice University, Houston, USA., Yaseen AB; Department of Bioengineering, Rice University, Houston, USA., Børen J; Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden., Gros R; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada; Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5B7, Canada., Bao G; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA; Department of Bioengineering, Rice University, Houston, USA., Boffa MB; Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5B7, Canada; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada. Electronic address: mlk@robarts.ca., Koschinsky ML; Robarts Research Institute, Schulich School of Medicine & Dentistry, London, Ontario, Canada; Department of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5B7, Canada. Electronic address: mboffa@uwo.ca.
Source: Atherosclerosis [Atherosclerosis] 2023 Nov; Vol. 384, pp. 117150. Date of Electronic Publication: 2023 May 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-1484
DOI:10.1016/j.atherosclerosis.2023.05.019