Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing.

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Title: Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing.
Authors: Grotzinger AD; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder.; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder., Singh K; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee., Miller-Fleming TW; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee., Lam M; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston.; Division of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York.; Research Division, Institute of Mental Health Singapore, Singapore.; Human Genetics, Genome Institute of Singapore, Singapore., Mallard TT; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston.; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston., Chen Y; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston.; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China., Liu Z; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston.; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston., Ge T; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston.; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston., Smoller JW; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston.; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston.
Source: JAMA psychiatry [JAMA Psychiatry] 2023 Aug 01; Vol. 80 (8), pp. 811-821.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589550 Publication Model: Print Cited Medium: Internet ISSN: 2168-6238 (Electronic) Linking ISSN: 2168622X NLM ISO Abbreviation: JAMA Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2168-6238
DOI:10.1001/jamapsychiatry.2023.1808