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Gut microbiome composition may be an indicator of preclinical Alzheimer's disease.

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Title: Gut microbiome composition may be an indicator of preclinical Alzheimer's disease.
Authors: Ferreiro AL; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Choi J; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ryou J; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Newcomer EP; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA., Thompson R; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Bollinger RM; Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO 63110, USA., Hall-Moore C; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Ndao IM; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Sax L; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Stark SL; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA., Fagan AM; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Cruchaga C; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; NeuroGenomics and Informatics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Butt OH; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Tarr PI; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ances BM; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Dantas G; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.; Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Source: Science translational medicine [Sci Transl Med] 2023 Jun 14; Vol. 15 (700), pp. eabo2984. Date of Electronic Publication: 2023 Jun 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.abo2984