Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.

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Title: Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.
Authors: Jha D; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Al-Taie Z; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, New York City, NY, USA., Krek A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, NY, USA., Eshghi ST; Biomarker Discovery, OMNI, Genentech Inc. South SanFrancisco, CA, USA.; OMNI Biomarker Development, Genentech Inc. South SanFrancisco, CA, USA., Fantou A; Université de Nantes, Inserm, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France., Laurent T; Université de Nantes, Inserm, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France., Tankelevich M; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cao X; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, NY, USA., Meringer H; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Livanos AE; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tokuyama M; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cossarini F; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bourreille A; Université de Nantes, Inserm, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France., Josien R; Université de Nantes, Inserm, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France., Hou R; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, New York City, NY, USA., Canales-Herrerias P; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ungaro RC; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kayal M; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Marion J; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Polydorides AD; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ko HM; Department of Pathology and Cell Biology, Columbia University Medical Center-New York Presbyterian Hospital, New York, New York., D'souza D; Human Immune Monitoring Core, Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Merand R; Human Immune Monitoring Core, Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kim-Schulze S; Human Immune Monitoring Core, Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hackney JA; Biomarker Discovery, OMNI, Genentech Inc. South SanFrancisco, CA, USA.; OMNI Biomarker Development, Genentech Inc. South SanFrancisco, CA, USA., Nguyen A; Biomarker Discovery, OMNI, Genentech Inc. South SanFrancisco, CA, USA.; OMNI Biomarker Development, Genentech Inc. South SanFrancisco, CA, USA., McBride JM; Biomarker Discovery, OMNI, Genentech Inc. South SanFrancisco, CA, USA.; OMNI Biomarker Development, Genentech Inc. South SanFrancisco, CA, USA., Yuan GC; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, NY, USA., Colombel JF; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Martin JC; Université de Nantes, Inserm, CHU Nantes, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France., Argmann C; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, New York City, NY, USA., Suárez-Fariñas M; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Institute for Data Science and Genomic Technology, New York City, NY, USA., Petralia F; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, NY, USA., Mehandru S; Henry D. Janowitz Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Institute of Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 05. Date of Electronic Publication: 2023 Jun 05.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2023.06.02.542863