Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition.

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Bibliographic Details
Title: Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition.
Authors: Gao CW; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD., Lin W; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Riddle RC; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.; Research and Development Service, Baltimore Veterans Administration Medical Center, Baltimore, MD., Kushwaha P; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD., Boukas L; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD., Björnsson HT; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.; Landspítali University Hospital, Reykjavík, Iceland., Hansen KD; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD., Fahrner JA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 30. Date of Electronic Publication: 2023 Jun 30.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2023.06.23.546270