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Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.

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Title: Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.
Authors: Huang Q; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Chen AT; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Biological and Biomedical Sciences, Harvard University, Cambridge, Massachusetts, United States of America., Chan KY; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Sorensen H; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Barry AJ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Azari B; Electrical & Computer Engineering Department, Northeastern University, Boston, Massachusetts, United States of America., Zheng Q; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Beddow T; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Zhao B; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Tobey IG; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Moncada-Reid C; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Eid FE; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Department of Systems and Computer Engineering, Al-Azhar University, Cairo, Egypt., Walkey CJ; Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America., Ljungberg MC; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas, United States of America., Lagor WR; Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America., Heaney JD; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America., Chan YA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America., Deverman BE; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Source: PLoS biology [PLoS Biol] 2023 Jul 19; Vol. 21 (7), pp. e3002112. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier.
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  Data: <searchLink fieldCode="AU" term="%22Huang+Q%22">Huang Q</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Chen+AT%22">Chen AT</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Biological and Biomedical Sciences, Harvard University, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Chan+KY%22">Chan KY</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Sorensen+H%22">Sorensen H</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Barry+AJ%22">Barry AJ</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Azari+B%22">Azari B</searchLink>; Electrical & Computer Engineering Department, Northeastern University, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Zheng+Q%22">Zheng Q</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Beddow+T%22">Beddow T</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhao+B%22">Zhao B</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Tobey+IG%22">Tobey IG</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Moncada-Reid+C%22">Moncada-Reid C</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Eid+FE%22">Eid FE</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Department of Systems and Computer Engineering, Al-Azhar University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Walkey+CJ%22">Walkey CJ</searchLink>; Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Ljungberg+MC%22">Ljungberg MC</searchLink>; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America.; Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Lagor+WR%22">Lagor WR</searchLink>; Department of Integrative Physiology, Baylor College of Medicine, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Heaney+JD%22">Heaney JD</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Chan+YA%22">Chan YA</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Deverman+BE%22">Deverman BE</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2023 Jul 19; Vol. 21 (7), pp. e3002112. <i>Date of Electronic Publication: </i>2023 Jul 19 (<i>Print Publication: </i>2023).
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