Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.

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Title: Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum.
Authors: Lee DSM; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL., Cardone KM; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Zhang DY; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Tsao NL; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Abramowitz S; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Sharma P; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., DePaolo JS; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Conery M; Genomics and Computational Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Aragam KG; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA., Biddinger K; Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA., Dilitikas O; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Hoffman-Andrews L; Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Judy RL; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Khan A; Division of Nephrology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY., Kulo I; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Puckelwartz MJ; Department of Pharmacology, Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL., Reza N; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Satterfield BA; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN., Singhal P; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Arany ZP; Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Cappola TP; Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Carruth E; Department of Translational Data Science and Informatics, Geisinger, Danville, PA., Day SM; Division of Cardiovascular Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Do R; The Charles Bronfman Institute for Personalized Medicine, Mount Sinai Icahn School of Medicine, New York, NY.; Biome Phenomics Center, Mount Sinai Icahn School of Medicine, New York, NY.; Department of Genetics and Genomic Sciences, Mount Sinai Icahn School of Medicine, New York, NY., Haggarty CM; Department of Translational Data Science and Informatics, Geisinger, Danville, PA., Joseph J; Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., McNally EM; Center for Genetic Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL., Nadkarni G; Division of Nephrology, Department of Medicine, Mount Sinai Icahn School of Medicine, New York, NY., Owens AT; Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Rader DJ; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Ritchie MD; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Institute for Biomedical Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA.; Atlanta VA Health Care System, Decatur, GA., Voight BF; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA., Levin MG; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA., Damrauer SM; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA.
Corporate Authors: Regeneron Genetics Center
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Oct 23. Date of Electronic Publication: 2024 Oct 23.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA.; Atlanta VA Health Care System, Decatur, GA.<br /><searchLink fieldCode="AU" term="%22Voight+BF%22">Voight BF</searchLink>; Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Corporal Michael J. 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