Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.

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Title: Clonally expanded CD38hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.
Authors: Wang R; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Shanghai Institute of Rheumatology/Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China., Singaraju A; HSS Research Institute, Hospital for Special Surgery, New York, NY 10021, USA.; Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Marks KE; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Shakib L; HSS Research Institute, Hospital for Special Surgery, New York, NY 10021, USA.; Graduate Program in Physiology, Biophysics and Systems Biology, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Dunlap G; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA., Adejoorin I; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Greisen SR; Department of Biomedicine, Aarhus University / Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark., Chen L; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Tirpack AK; Medical School at Campbell University School of Osteopathic Medicine, Lillington, NC 27546, USA., Aude C; Division of Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY 10021, USA., Fein MR; HSS Research Institute, Hospital for Special Surgery, New York, NY 10021, USA., Todd DJ; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., MacFarlane L; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Goodman SM; Division of Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY 10021, USA., DiCarlo EF; Division of Pathology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY 10021, USA., Massarotti EM; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Sparks JA; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Jonsson AH; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Brenner MB; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Postow MA; Melanoma Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Chan KK; Division of Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY 10021, USA., Bass AR; Division of Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY 10021, USA., Donlin LT; HSS Research Institute, Hospital for Special Surgery, New York, NY 10021, USA.; Graduate Program in Physiology, Biophysics and Systems Biology, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Rao DA; Division of Rheumatology, Inflammation, Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Source: Science immunology [Sci Immunol] 2023 Jul 28; Vol. 8 (85), pp. eadd1591. Date of Electronic Publication: 2023 Jul 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2470-9468
DOI:10.1126/sciimmunol.add1591