Safety, Reactogenicity, Immunogenicity, and Dose Selection of 10-Valent Extraintestinal Pathogenic Escherichia coli Bioconjugate Vaccine (VAC52416) in Adults Aged 60-85 Years in a Randomized, Multicenter, Interventional, First-in-Human, Phase 1/2a Study.
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| Title: | Safety, Reactogenicity, Immunogenicity, and Dose Selection of 10-Valent Extraintestinal Pathogenic Escherichia coli Bioconjugate Vaccine (VAC52416) in Adults Aged 60-85 Years in a Randomized, Multicenter, Interventional, First-in-Human, Phase 1/2a Study. |
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| Authors: | Fierro CA; Johnson County Clin-Trials, Lenexa, Kansas, USA., Sarnecki M; Infectious Diseases and Vaccines, Janssen Research and Development, Janssen Vaccines, Bern, Switzerland., Doua J; Infectious Diseases and Vaccines, Janssen Research and Development, Janssen Pharmaceutica, Beerse, Belgium., Spiessens B; Infectious Diseases and Vaccines, Janssen Research and Development, Janssen Pharmaceutica, Beerse, Belgium., Go O; Janssen Research and Development, Raritan, New Jersey, USA., Davies TA; Janssen Research and Development, Raritan, New Jersey, USA., van den Dobbelsteen G; Bacterial Vaccines Discovery and Early Development, Janssen Vaccines and Prevention B.V., Leiden, The Netherlands., Poolman J; Bacterial Vaccines Discovery and Early Development, Janssen Vaccines and Prevention B.V., Leiden, The Netherlands., Abbanat D; Janssen Research and Development, Raritan, New Jersey, USA., Haazen W; Infectious Diseases and Vaccines, Janssen Research and Development, Janssen Pharmaceutica, Beerse, Belgium. |
| Source: | Open forum infectious diseases [Open Forum Infect Dis] 2023 Aug 11; Vol. 10 (8), pp. ofad417. Date of Electronic Publication: 2023 Aug 11 (Print Publication: 2023). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2328-8957 |
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| DOI: | 10.1093/ofid/ofad417 |