Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).

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Bibliographic Details
Title: Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Authors: Ferguson MR; Department of Molecular Sciences, Abbratech, Branford, CT, United States., Delgado KN; Department of Medicine, UConn Health, Farmington, CT, United States., McBride S; Research and Development Abcam, Branford, CT, United States., Orbe IC; Department of Pediatrics, UConn Health, Farmington, CT, United States., La Vake CJ; Department of Pediatrics, UConn Health, Farmington, CT, United States., Caimano MJ; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States., Mendez Q; Department of Molecular Sciences, Abbratech, Branford, CT, United States., Moraes TF; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Schryvers AB; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, AB, Canada., Moody MA; Duke Human Vaccine Institute, Durham, NC, United States.; Department of Pediatrics, Duke University Medical Center, Durham, NC, United States.; Department of Integrative Immunobiology, Duke University Medical Center, Durham, NC, United States., Radolf JD; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.; Department of Immunology, UConn Health, Farmington, CT, United States.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, United States., Weiner MP; Department of Molecular Sciences, Abbratech, Branford, CT, United States., Hawley KL; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Immunology, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases and Immunology, Connecticut Children's, Hartford, CT, United States.
Source: Frontiers in immunology [Front Immunol] 2023 Aug 22; Vol. 14, pp. 1222267. Date of Electronic Publication: 2023 Aug 22 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-3224
DOI:10.3389/fimmu.2023.1222267