Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours.
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| Title: | Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours. |
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| Authors: | Maekawa N; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Cancer Research Unit, One Health Research Center, Hokkaido University, Sapporo, Japan., Konnai S; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Cancer Research Unit, One Health Research Center, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Department of Disease Control, Hokkaido University, Sapporo, Japan.; Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Japan., Hosoya K; Cancer Research Unit, One Health Research Center, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Kim S; Cancer Research Unit, One Health Research Center, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Kinoshita R; Cancer Research Unit, One Health Research Center, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Deguchi T; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan.; Department of Companion Animal Clinical Sciences, Companion Animal Internal Medicine, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan., Owaki R; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Tachibana Y; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Yokokawa M; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan., Takeuchi H; Faculty of Veterinary Medicine, Department of Disease Control, Hokkaido University, Sapporo, Japan., Kagawa Y; North Lab, Sapporo, Japan., Takagi S; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan.; Department of Veterinary Surgery 1, School of Veterinary Medicine, Azabu University, Sagamihara, Japan., Ohta H; Faculty of Veterinary Medicine, Veterinary Teaching Hospital, Hokkaido University, Sapporo, Japan.; Department of Companion Animal Clinical Sciences, Companion Animal Internal Medicine, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan., Kato Y; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan., Yamamoto S; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Fuso Pharmaceutical Industries, Ltd., Osaka, Japan., Yamamoto K; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Fuso Pharmaceutical Industries, Ltd., Osaka, Japan., Suzuki Y; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Institute for Vaccine Research and Development (HU-IVReD), Hokkaido University, Sapporo, Japan.; International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.; Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Japan., Okagawa T; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan., Murata S; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Department of Disease Control, Hokkaido University, Sapporo, Japan., Ohashi K; Faculty of Veterinary Medicine, Department of Advanced Pharmaceutics, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, Department of Disease Control, Hokkaido University, Sapporo, Japan.; Faculty of Veterinary Medicine, International Affairs Office, Hokkaido University, Sapporo, Japan. |
| Source: | PloS one [PLoS One] 2023 Oct 04; Vol. 18 (10), pp. e0291727. Date of Electronic Publication: 2023 Oct 04 (Print Publication: 2023). |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0291727 |
