CRISPR deletion of a SINE-VNTR-Alu (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the MAPT locus.

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Title:	CRISPR deletion of a SINE-VNTR-Alu (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the MAPT locus.
Authors:	Fröhlich A; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.; Perron Institute for Neurological and Translational Science, Perth, WA, Australia., Hughes LS; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Middlehurst B; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Pfaff AL; Perron Institute for Neurological and Translational Science, Perth, WA, Australia.; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, WA, Australia., Bubb VJ; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Koks S; Perron Institute for Neurological and Translational Science, Perth, WA, Australia.; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, WA, Australia., Quinn JP; Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Source:	Frontiers in neurology [Front Neurol] 2023 Sep 29; Vol. 14, pp. 1273036. Date of Electronic Publication: 2023 Sep 29 (Print Publication: 2023).
Publication Type:	Journal Article
Journal Info:	Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1664-2295
DOI:	10.3389/fneur.2023.1273036