Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain.
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| Title: | Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain. |
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| Authors: | Ikenuma H; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Ogata A; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science (GUMS), Kani, Japan., Koyama H; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan., Ji B; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.; Department of Radiopharmacy and Molecular Imaging, School of Pharmacy, Fudan University, Shanghai, China., Ishii H; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Yamada T; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Abe J; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Seki C; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Nagai Y; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Ichise M; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Minamimoto T; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Higuchi M; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Zhang MR; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Kato T; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Ito K; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Suzuki M; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan., Kimura Y; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan. yazkim@ncgg.go.jp.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan. yazkim@ncgg.go.jp. |
| Source: | EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2023 Oct 18; Vol. 8 (1), pp. 31. Date of Electronic Publication: 2023 Oct 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2365-421X |
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| DOI: | 10.1186/s41181-023-00217-z |
