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Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain.

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Title: Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain.
Authors: Ikenuma H; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Ogata A; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science (GUMS), Kani, Japan., Koyama H; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan., Ji B; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.; Department of Radiopharmacy and Molecular Imaging, School of Pharmacy, Fudan University, Shanghai, China., Ishii H; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Yamada T; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Abe J; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Seki C; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Nagai Y; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Ichise M; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Minamimoto T; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Higuchi M; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Zhang MR; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan., Kato T; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Ito K; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan., Suzuki M; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan., Kimura Y; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan. yazkim@ncgg.go.jp.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan. yazkim@ncgg.go.jp.
Source: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2023 Oct 18; Vol. 8 (1), pp. 31. Date of Electronic Publication: 2023 Oct 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain.
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  Data: <searchLink fieldCode="AU" term="%22Ikenuma+H%22">Ikenuma H</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Ogata+A%22">Ogata A</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Pharmacy, Faculty of Pharmacy, Gifu University of Medical Science (GUMS), Kani, Japan.<br /><searchLink fieldCode="AU" term="%22Koyama+H%22">Koyama H</searchLink>; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan.<br /><searchLink fieldCode="AU" term="%22Ji+B%22">Ji B</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.; Department of Radiopharmacy and Molecular Imaging, School of Pharmacy, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ishii+H%22">Ishii H</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+T%22">Yamada T</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Abe+J%22">Abe J</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Seki+C%22">Seki C</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Nagai+Y%22">Nagai Y</searchLink>; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Ichise+M%22">Ichise M</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Minamimoto+T%22">Minamimoto T</searchLink>; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Higuchi+M%22">Higuchi M</searchLink>; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Zhang+MR%22">Zhang MR</searchLink>; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+T%22">Kato T</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+K%22">Ito K</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+M%22">Suzuki M</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.; Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+Y%22">Kimura Y</searchLink>; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology (NCGG), 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan. yazkim@ncgg.go.jp.; Department of Functional Brain Imaging, National Institutes for Quantum Science and Technology (QST), Chiba, Japan. yazkim@ncgg.go.jp.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Open%22">Springer Open </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101714628 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2365-421X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222365421X%22">2365421X </searchLink><i>NLM ISO Abbreviation: </i>EJNMMI Radiopharm Chem <i>Subsets: </i>PubMed not MEDLINE
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