Raising NAD+ Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.

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Title: Raising NAD+ Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.
Authors: Walker MA; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Chen H; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle.; Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China (H.C.)., Yadav A; Department of Pharmaceutics, School of Pharmacy (A.V., N. I.), University of Washington, Seattle., Ritterhoff J; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Villet O; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., McMillen T; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Wang Y; Department of Computer Science & Engineering (Y.W.), University of Washington, Seattle., Purcell H; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Djukovic D; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Raftery D; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle., Isoherranen N; Department of Pharmaceutics, School of Pharmacy (A.V., N. I.), University of Washington, Seattle., Tian R; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine (M.A.W., H.C., J.R., O.V., T.M., H.P., D.D., D.R., R.T.), University of Washington, Seattle.
Source: Circulation [Circulation] 2023 Dec 19; Vol. 148 (25), pp. 2038-2057. Date of Electronic Publication: 2023 Nov 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4539
DOI:10.1161/CIRCULATIONAHA.123.066039