Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes.

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Title: Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes.
Authors: Harley J; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Santosa MM; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Ng CY; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Grinchuk OV; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Hor JH; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Liang Y; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Lim VJ; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore., Tee WW; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Ong DST; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Ng SY; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore, 138673, Singapore. syng@imcb.a-star.edu.sg.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore. syng@imcb.a-star.edu.sg.
Source: Biogerontology [Biogerontology] 2024 Apr; Vol. 25 (2), pp. 341-360. Date of Electronic Publication: 2023 Nov 21.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 100930043 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6768 (Electronic) Linking ISSN: 13895729 NLM ISO Abbreviation: Biogerontology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1573-6768
DOI:10.1007/s10522-023-10076-5