Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome.

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Title: Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome.
Authors: Edwards NC; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA.; Department of Neuroscience, Columbia University, New York City, NY, USA., Lao PJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Alshikho MJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Ericsson OM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Rizvi B; Department of Neurobiology & Behavior, University of California, Irvine, CA, USA., Petersen ME; University of North Texas Health Science Center, Fort Worth, TX, USA., O'Bryant S; University of North Texas Health Science Center, Fort Worth, TX, USA., Flores-Aguilar L; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA, USA., Simoes S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Mapstone M; Department of Neurology, University of California, Irvine, CA, USA., Tudorascu DL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Christian BT; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Lee JH; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Lai F; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA., Rosas HD; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.; Department of Radiology, Center for Neuroimaging of Aging and neurodegenerative Diseases, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA., Zaman S; Department of Psychiatry, University of Cambridge, Cambridge, UK., Lott IT; Department of Pediatrics and Neurology, School of Medicine, University of California, Irvine, CA, USA., Yassa MA; Department of Neurobiology & Behavior, University of California, Irvine, CA, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA, USA., Gutierrez J; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA., Wilcock DM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.; Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA., Head E; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA, USA., Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Nov 30. Date of Electronic Publication: 2023 Nov 30.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.1101/2023.11.28.23298693