Effective substances and molecular mechanisms guided by network pharmacology: An example study of Scrophulariae Radix treatment of hyperthyroidism and thyroid hormone-induced liver and kidney injuries.

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Title: Effective substances and molecular mechanisms guided by network pharmacology: An example study of Scrophulariae Radix treatment of hyperthyroidism and thyroid hormone-induced liver and kidney injuries.
Authors: Sheng MY; School of Pharmacy, Hubei University of Traditional Chinese Medicine, Wuhan, 430065, China; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Institute for Drug Control, Wuhan, 430064, China; Department of Anatomy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 717069153@qq.com., Peng DW; Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: pengdewei_1995@163.com., Peng HM; Department of Anatomy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: hmpeng2003@hust.edu.cn., Zhang YL; School of Pharmacy, Hubei University of Traditional Chinese Medicine, Wuhan, 430065, China. Electronic address: 2396734884@qq.com., Xiao L; Hubei Institute for Drug Control, Wuhan, 430064, China. Electronic address: 469851167@qq.com., Zhang MR; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 2651840687@qq.com., Wang SY; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 1226773103@qq.com., Zhao CP; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 1484070596@qq.com., Zhu SY; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 1351857479@qq.com., Lu JK; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: 2351862839@qq.com., Lin L; Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: linli@tjh.tjmu.edu.cn., Huang R; Department of Ophthalmology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, Hubei, China; Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, China. Electronic address: 1317951740@qq.com., Nie J; School of Pharmacy, Hubei University of Traditional Chinese Medicine, Wuhan, 430065, China; Hubei Institute for Drug Control, Wuhan, 430064, China. Electronic address: niejingwh@sina.com., Fang JB; School of Pharmacy, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. Electronic address: fangjb@hust.edu.cn.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2024 May 23; Vol. 326, pp. 117965. Date of Electronic Publication: 2024 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7573
DOI:10.1016/j.jep.2024.117965