BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer.
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| Title: | BCL-X |
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| Authors: | Jenkins LJ; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Luk IY; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Chionh F; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Tan T; Personalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia., Needham K; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Ayton J; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Reehorst CM; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Vukelic N; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia., Sieber OM; Personalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, Melbourne, VIC, Australia.; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia., Mouradov D; Personalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia., Gibbs P; Personalised Oncology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia., Williams DS; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Pathology, Austin Health, Melbourne, VIC, Australia., Tebbutt NC; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, Melbourne, VIC, Australia.; Department of Medical Oncology, Austin Health, Melbourne, Australia., Desai J; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Hollande F; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia.; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Melbourne, VIC, Australia., Dhillon AS; The institute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, Australia., Lee EF; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Merino D; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia.; Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia., Fairlie WD; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia.; Department of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Mariadason JM; Olivia Newton-John Cancer Research Institute, Melbourne, VIC, Australia. john.mariadason@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, VIC, Australia. john.mariadason@onjcri.org.au. |
| Source: | Cell death & disease [Cell Death Dis] 2024 Mar 01; Vol. 15 (3), pp. 183. Date of Electronic Publication: 2024 Mar 01. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-024-06478-z |
