Complete chromosome 21 centromere sequencing of families with Down syndrome reveals centromere size asymmetry.

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Title: Complete chromosome 21 centromere sequencing of families with Down syndrome reveals centromere size asymmetry.
Authors: Mastrorosa FK; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Daponte A; Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, 70124, Italy., Wertz J; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Rozanski AN; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Harvey WT; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Porubsky D; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Knuth J; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Garcia GH; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Ayllon M; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Munson KM; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., Hoekzema K; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA., He W; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA., Sherman SL; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA., Allen EG; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA., Rosser TC; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA., Catacchio CR; Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, 70124, Italy., Ventura M; Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, 70124, Italy., Logsdon GA; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.; Department of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, 70124, Italy., Eichler EE; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 16. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2024.02.25.581464