Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus.

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Title: Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus.
Authors: Lin GL; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK. gulung.lin.oxford@gmail.com.; NIHR Oxford Biomedical Research Centre, Oxford, UK. gulung.lin.oxford@gmail.com., Drysdale SB; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.; Centre for Neonatal and Paediatric Infection, Institute for Infection and Immunity, St George's, University of London, London, UK., Snape MD; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., O'Connor D; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Brown A; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK., MacIntyre-Cockett G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Mellado-Gomez E; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Wellcome Sanger Institute, Hinxton, UK., de Cesare M; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Human Technopole, Milan, Italy., Ansari MA; Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Bonsall D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bray JE; Department of Biology, University of Oxford, Oxford, UK., Jolley KA; Department of Biology, University of Oxford, Oxford, UK., Bowden R; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Aerssens J; Translational Biomarkers, Infectious Diseases Therapeutic Area, Janssen Pharmaceutica NV, Beerse, Belgium., Bont L; Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, Netherlands.; ReSViNET Foundation, Zeist, Netherlands., Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK., Martinon-Torres F; Translational Pediatrics and Infectious Diseases, Pediatrics Department, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.; Genetics, Vaccines, Infectious Diseases and Pediatrics Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, University of Santiago de Compostela, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Nair H; Centre for Global Health, Usher Institute, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Golubchik T; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK. tanya.golubchik@sydney.edu.au.; Sydney Infectious Diseases Institute, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia. tanya.golubchik@sydney.edu.au., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.
Corporate Authors: RESCEU Consortium
Source: Nature communications [Nat Commun] 2024 Mar 16; Vol. 15 (1), pp. 2379. Date of Electronic Publication: 2024 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-024-46648-3