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Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis.

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Title: Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis.
Authors: Middha P; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Thummalapalli R; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Betti MJ; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Yao L; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Quandt Z; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Diabetes Center, University of California San Francisco, San Francisco, CA, USA., Balaratnam K; Princess Margaret Cancer Centre, Toronto, ON, Canada., Bejan CA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Cardenas E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Falcon CJ; Fiona and Stanley Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Faleck DM; Gastroenterology, Hepatology & Nutrition Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gubens MA; Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Huntsman S; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Johnson DB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kachuri L; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cancer Institute, Stanford University of Medicine, Stanford, CA, USA., Khan K; Princess Margaret Cancer Centre, Toronto, ON, Canada., Li M; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Lovly CM; Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN, USA., Murray MH; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Patel D; Princess Margaret Cancer Centre, Toronto, ON, Canada., Werking K; Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Xu Y; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Zhan LJ; Princess Margaret Cancer Centre, Toronto, ON, Canada., Balko JM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Liu G; Princess Margaret Cancer Centre, Toronto, ON, Canada.; Temerty School of Medicine, Toronto, ON, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Aldrich MC; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Schoenfeld AJ; Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ziv E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.; Center for Genes, Environment and Health, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.
Corporate Authors: Princess Margaret Lung Group
Source: Nature communications [Nat Commun] 2024 Mar 26; Vol. 15 (1), pp. 2568. Date of Electronic Publication: 2024 Mar 26.
Publication Type: Meta-Analysis; Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Elad.Ziv@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.; Center for Genes, Environment and Health, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA. Elad.Ziv@ucsf.edu.
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