Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.

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Title: Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
Authors: Satti I; The Jenner Institute, University of Oxford, Oxford, UK., Marshall JL; The Jenner Institute, University of Oxford, Oxford, UK., Harris SA; The Jenner Institute, University of Oxford, Oxford, UK., Wittenberg R; The Jenner Institute, University of Oxford, Oxford, UK., Tanner R; The Jenner Institute, University of Oxford, Oxford, UK., Lopez Ramon R; The Jenner Institute, University of Oxford, Oxford, UK., Wilkie M; The Jenner Institute, University of Oxford, Oxford, UK., Ramos Lopez F; The Jenner Institute, University of Oxford, Oxford, UK., Riste M; The Jenner Institute, University of Oxford, Oxford, UK., Wright D; The Jenner Institute, University of Oxford, Oxford, UK., Peralta Alvarez MP; The Jenner Institute, University of Oxford, Oxford, UK., Williams N; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Morrison H; The Jenner Institute, University of Oxford, Oxford, UK., Stylianou E; The Jenner Institute, University of Oxford, Oxford, UK., Folegatti P; The Jenner Institute, University of Oxford, Oxford, UK., Jenkin D; The Jenner Institute, University of Oxford, Oxford, UK., Vermaak S; The Jenner Institute, University of Oxford, Oxford, UK., Rask L; The Jenner Institute, University of Oxford, Oxford, UK., Cabrera Puig I; The Jenner Institute, University of Oxford, Oxford, UK., Powell Doherty R; The Jenner Institute, University of Oxford, Oxford, UK., Lawrie A; The Jenner Institute, University of Oxford, Oxford, UK., Moss P; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Hinks T; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Bettinson H; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., McShane H; The Jenner Institute, University of Oxford, Oxford, UK. Electronic address: helen.mcshane@ndm.ox.ac.uk.
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Aug; Vol. 24 (8), pp. 909-921. Date of Electronic Publication: 2024 Apr 12.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-4457
DOI:10.1016/S1473-3099(24)00143-9