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Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.

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Title: Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
Authors: Satti I; The Jenner Institute, University of Oxford, Oxford, UK., Marshall JL; The Jenner Institute, University of Oxford, Oxford, UK., Harris SA; The Jenner Institute, University of Oxford, Oxford, UK., Wittenberg R; The Jenner Institute, University of Oxford, Oxford, UK., Tanner R; The Jenner Institute, University of Oxford, Oxford, UK., Lopez Ramon R; The Jenner Institute, University of Oxford, Oxford, UK., Wilkie M; The Jenner Institute, University of Oxford, Oxford, UK., Ramos Lopez F; The Jenner Institute, University of Oxford, Oxford, UK., Riste M; The Jenner Institute, University of Oxford, Oxford, UK., Wright D; The Jenner Institute, University of Oxford, Oxford, UK., Peralta Alvarez MP; The Jenner Institute, University of Oxford, Oxford, UK., Williams N; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Morrison H; The Jenner Institute, University of Oxford, Oxford, UK., Stylianou E; The Jenner Institute, University of Oxford, Oxford, UK., Folegatti P; The Jenner Institute, University of Oxford, Oxford, UK., Jenkin D; The Jenner Institute, University of Oxford, Oxford, UK., Vermaak S; The Jenner Institute, University of Oxford, Oxford, UK., Rask L; The Jenner Institute, University of Oxford, Oxford, UK., Cabrera Puig I; The Jenner Institute, University of Oxford, Oxford, UK., Powell Doherty R; The Jenner Institute, University of Oxford, Oxford, UK., Lawrie A; The Jenner Institute, University of Oxford, Oxford, UK., Moss P; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Hinks T; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Bettinson H; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., McShane H; The Jenner Institute, University of Oxford, Oxford, UK. Electronic address: helen.mcshane@ndm.ox.ac.uk.
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Aug; Vol. 24 (8), pp. 909-921. Date of Electronic Publication: 2024 Apr 12.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
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  Data: Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
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  Data: <searchLink fieldCode="AU" term="%22Satti+I%22">Satti I</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Marshall+JL%22">Marshall JL</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Harris+SA%22">Harris SA</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wittenberg+R%22">Wittenberg R</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tanner+R%22">Tanner R</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lopez+Ramon+R%22">Lopez Ramon R</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wilkie+M%22">Wilkie M</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ramos+Lopez+F%22">Ramos Lopez F</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Riste+M%22">Riste M</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wright+D%22">Wright D</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Peralta+Alvarez+MP%22">Peralta Alvarez MP</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Williams+N%22">Williams N</searchLink>; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Morrison+H%22">Morrison H</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Stylianou+E%22">Stylianou E</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Folegatti+P%22">Folegatti P</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jenkin+D%22">Jenkin D</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Vermaak+S%22">Vermaak S</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rask+L%22">Rask L</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cabrera+Puig+I%22">Cabrera Puig I</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Powell+Doherty+R%22">Powell Doherty R</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lawrie+A%22">Lawrie A</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Moss+P%22">Moss P</searchLink>; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Hinks+T%22">Hinks T</searchLink>; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bettinson+H%22">Bettinson H</searchLink>; Oxford Centre for Respiratory Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McShane+H%22">McShane H</searchLink>; The Jenner Institute, University of Oxford, Oxford, UK. Electronic address: helen.mcshane@ndm.ox.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101130150%22">The Lancet. Infectious diseases</searchLink> [Lancet Infect Dis] 2024 Aug; Vol. 24 (8), pp. 909-921. <i>Date of Electronic Publication: </i>2024 Apr 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101130150 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-4457 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214733099%22">14733099 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Infect Dis <i>Subsets: </i>MEDLINE
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