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The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.

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Title: The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
Authors: Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Dadi PK; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Kim J; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Department of Chemistry, Vanderbilt University, Nashville, United States., Dickerson MT; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Behera S; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Dobson JR; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Shrestha S; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Cartailler JP; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Sampson L; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Magnuson MA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, United States., Jacobson DA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.
Source: ELife [Elife] 2024 May 03; Vol. 12. Date of Electronic Publication: 2024 May 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
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  Data: <searchLink fieldCode="AU" term="%22Nakhe+AY%22">Nakhe AY</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Dadi+PK%22">Dadi PK</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Department of Chemistry, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Dickerson+MT%22">Dickerson MT</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Behera+S%22">Behera S</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Dobson+JR%22">Dobson JR</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Shrestha+S%22">Shrestha S</searchLink>; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Cartailler+JP%22">Cartailler JP</searchLink>; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Sampson+L%22">Sampson L</searchLink>; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Magnuson+MA%22">Magnuson MA</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, United States.<br /><searchLink fieldCode="AU" term="%22Jacobson+DA%22">Jacobson DA</searchLink>; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.
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  Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2024 May 03; Vol. 12. <i>Date of Electronic Publication: </i>2024 May 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE
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        Value: 10.7554/eLife.89967
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              Text: 2024 May 03
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