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Safety and efficacy of long-term sodium channel blocker therapy for early rhythm control: the EAST-AFNET 4 trial.

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Title: Safety and efficacy of long-term sodium channel blocker therapy for early rhythm control: the EAST-AFNET 4 trial.
Authors: Rillig A; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany., Eckardt L; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Department of Cardiology II-Electrophysiology, University Hospital Münster, Münster, Germany., Borof K; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany., Camm AJ; Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Institute, St. George's University of London, London, UK., Crijns HJGM; Department of Cardiology, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands., Goette A; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; St. Vincenz Hospital, Paderborn, Paderborn, Germany.; Working Group of Molecular Electrophysiology, University Hospital Magdeburg, Magdeburg, Germany., Breithardt G; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Department of Cardiology II-Electrophysiology, University Hospital Münster, Münster, Germany., Lemoine MD; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany., Metzner A; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany., Rottner L; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany., Schotten U; Department of Physiology, Maastricht University, Maastricht, The Netherlands., Vettorazzi E; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Wegscheider K; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Zapf A; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Heidbuchel H; Faculty of Medicine and Health Sciences, Department of Cardiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.; Faculty of Medicine and Health Sciences, Cardiovascular Research, GENCOR, Antwerp University, Antwerp, Belgium.; Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium., Willems S; Asklepios Klinik St. Georg, Klinik für Kardiologie und internistische Intensivmedizin, Hamburg, Germany., Fabritz L; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK., Schnabel RB; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany., Magnussen C; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany., Kirchhof P; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.
Source: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2024 Jun 03; Vol. 26 (6).
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Internet ISSN: 1532-2092 (Electronic) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and efficacy of long-term sodium channel blocker therapy for early rhythm control: the EAST-AFNET 4 trial.
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  Data: <searchLink fieldCode="AU" term="%22Rillig+A%22">Rillig A</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Eckardt+L%22">Eckardt L</searchLink>; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Department of Cardiology II-Electrophysiology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Borof+K%22">Borof K</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Camm+AJ%22">Camm AJ</searchLink>; Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Institute, St. George's University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Crijns+HJGM%22">Crijns HJGM</searchLink>; Department of Cardiology, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Goette+A%22">Goette A</searchLink>; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; St. Vincenz Hospital, Paderborn, Paderborn, Germany.; Working Group of Molecular Electrophysiology, University Hospital Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Breithardt+G%22">Breithardt G</searchLink>; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Department of Cardiology II-Electrophysiology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Lemoine+MD%22">Lemoine MD</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Metzner+A%22">Metzner A</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Rottner+L%22">Rottner L</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schotten+U%22">Schotten U</searchLink>; Department of Physiology, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vettorazzi+E%22">Vettorazzi E</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wegscheider+K%22">Wegscheider K</searchLink>; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zapf+A%22">Zapf A</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Heidbuchel+H%22">Heidbuchel H</searchLink>; Faculty of Medicine and Health Sciences, Department of Cardiology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.; Faculty of Medicine and Health Sciences, Cardiovascular Research, GENCOR, Antwerp University, Antwerp, Belgium.; Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.<br /><searchLink fieldCode="AU" term="%22Willems+S%22">Willems S</searchLink>; Asklepios Klinik St. Georg, Klinik für Kardiologie und internistische Intensivmedizin, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fabritz+L%22">Fabritz L</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Schnabel+RB%22">Schnabel RB</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Magnussen+C%22">Magnussen C</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kirchhof+P%22">Kirchhof P</searchLink>; Department of Cardiology, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.; German Center for Cardiovascular Research, Partner Site Hamburg/Luebeck/Kiel, Germany.; Atrial Fibrillation Network (AFNET), Mendelstraße 11, 48149 Münster, Germany.; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.
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