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Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus.

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Title: Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus.
Authors: Maleckis M; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Wibowo M; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark., Williams SE; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Gotfredsen CH; Department of Chemistry, Technical University of Denmark, Kemitorvet, Building 207, 2800 Kgs. Lyngby, Denmark., Sigrist R; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Souza LDO; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.; Sino-Danish Center for Education and Research (SDC), Aarhus University, Dalgas Avenue 4, Building 3410, 8000 Aarhus C, Denmark., Cowled MS; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark., Charusanti P; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Gren T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Saha S; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Moreira JMA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark., Weber T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark., Ding L; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark.
Source: ACS chemical biology [ACS Chem Biol] 2024 Jun 21; Vol. 19 (6), pp. 1303-1310. Date of Electronic Publication: 2024 May 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
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  Data: Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus.
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  Data: <searchLink fieldCode="AU" term="%22Maleckis+M%22">Maleckis M</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Wibowo+M%22">Wibowo M</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Williams+SE%22">Williams SE</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Gotfredsen+CH%22">Gotfredsen CH</searchLink>; Department of Chemistry, Technical University of Denmark, Kemitorvet, Building 207, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Sigrist+R%22">Sigrist R</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Souza+LDO%22">Souza LDO</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.; Sino-Danish Center for Education and Research (SDC), Aarhus University, Dalgas Avenue 4, Building 3410, 8000 Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Cowled+MS%22">Cowled MS</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Charusanti+P%22">Charusanti P</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Gren+T%22">Gren T</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Saha+S%22">Saha S</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Moreira+JMA%22">Moreira JMA</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Weber+T%22">Weber T</searchLink>; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Søltofts Plads, Building 220, 2800 Kgs. Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Ding+L%22">Ding L</searchLink>; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, 2800 Kgs. Lyngby, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101282906%22">ACS chemical biology</searchLink> [ACS Chem Biol] 2024 Jun 21; Vol. 19 (6), pp. 1303-1310. <i>Date of Electronic Publication: </i>2024 May 14.
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