Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.

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Title: Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.
Authors: Kashiwada T; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Takano R; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Ando F; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Kuroda S; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Miyabe Y; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Immunology and Parasitology, St. Marianna University School of Medicine, Kawasaki, Japan., Owada R; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Miyanaga A; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Asatsuma-Okumura T; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Hashiguchi M; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Kanazawa Y; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Yoshida H; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Seike M; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Gemma A; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Iwai Y; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
Source: Frontiers in pharmacology [Front Pharmacol] 2024 May 10; Vol. 15, pp. 1384733. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1663-9812
DOI:10.3389/fphar.2024.1384733