Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.

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Title: Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.
Authors: Kashiwada T; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Takano R; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Ando F; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Kuroda S; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Miyabe Y; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Immunology and Parasitology, St. Marianna University School of Medicine, Kawasaki, Japan., Owada R; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Miyanaga A; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Asatsuma-Okumura T; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Hashiguchi M; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan., Kanazawa Y; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Yoshida H; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Seike M; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Gemma A; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan., Iwai Y; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
Source: Frontiers in pharmacology [Front Pharmacol] 2024 May 10; Vol. 15, pp. 1384733. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients.
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  Data: <searchLink fieldCode="AU" term="%22Kashiwada+T%22">Kashiwada T</searchLink>; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takano+R%22">Takano R</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ando+F%22">Ando F</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kuroda+S%22">Kuroda S</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyabe+Y%22">Miyabe Y</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.; Department of Immunology and Parasitology, St. Marianna University School of Medicine, Kawasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Owada+R%22">Owada R</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Miyanaga+A%22">Miyanaga A</searchLink>; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Asatsuma-Okumura+T%22">Asatsuma-Okumura T</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hashiguchi+M%22">Hashiguchi M</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kanazawa+Y%22">Kanazawa Y</searchLink>; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+H%22">Yoshida H</searchLink>; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Seike+M%22">Seike M</searchLink>; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Gemma+A%22">Gemma A</searchLink>; Department of Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Iwai+Y%22">Iwai Y</searchLink>; Department of Cell Biology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2024 May 10; Vol. 15, pp. 1384733. <i>Date of Electronic Publication: </i>2024 May 10 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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