Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use.

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Title: Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use.
Authors: Dao K; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Buettcher M; Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland.; Pediatric Infectious Diseases, Children's Hospital of Central Switzerland (KidZ), Lucerne, Switzerland.; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland., Golhen K; Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland., Kost J; Department of Pharmaceutical Sciences, Division of Pharmaceutical Technology, University of Basel, Basel, Switzerland., Schittny A; Department of Pharmaceutical Sciences, Division of Pharmaceutical Technology, University of Basel, Basel, Switzerland., Duthaler U; Division of Clinical Pharmacology & Toxicology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.; Division of Clinical Pharmacology & Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Atkinson A; Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland.; Division of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Haefliger D; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Guidi M; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Bardinet C; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Chtioui H; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Boulekbache A; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Buclin T; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Huwyler J; Department of Pharmaceutical Sciences, Division of Pharmaceutical Technology, University of Basel, Basel, Switzerland., Pfister M; Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland., Rothuizen LE; Clinical Pharmacology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Source: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Oct; Vol. 64 (10), pp. 1295-1303. Date of Electronic Publication: 2024 May 30.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1552-4604
DOI:10.1002/jcph.2462