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DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer.

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Title: DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer.
Authors: Momeny M; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland. majid.momeny@uth.tmc.edu.; The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA. majid.momeny@uth.tmc.edu., Tienhaara M; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Sharma M; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Chakroborty D; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Varjus R; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland., Takala I; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Merisaari J; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland., Padzik A; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland., Vogt A; University of Pittsburgh Drug Discovery Institute, Department of Computational and Systems Biology, Pittsburgh Technology Center, Pittsburgh, PA, USA., Paatero I; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland., Elenius K; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Laajala TD; Department of Mathematics and Statistics, University of Turku, Turku, Finland., Kurppa KJ; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Westermarck J; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland. jukwes@utu.fi.; Institute of Biomedicine, University of Turku, Turku, Finland. jukwes@utu.fi.
Source: EMBO molecular medicine [EMBO Mol Med] 2024 Jul; Vol. 16 (7), pp. 1603-1629. Date of Electronic Publication: 2024 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Momeny+M%22">Momeny M</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland. majid.momeny@uth.tmc.edu.; The Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA. majid.momeny@uth.tmc.edu.<br /><searchLink fieldCode="AU" term="%22Tienhaara+M%22">Tienhaara M</searchLink>; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Sharma+M%22">Sharma M</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Chakroborty+D%22">Chakroborty D</searchLink>; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Varjus+R%22">Varjus R</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Takala+I%22">Takala I</searchLink>; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Merisaari+J%22">Merisaari J</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Padzik+A%22">Padzik A</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Vogt+A%22">Vogt A</searchLink>; University of Pittsburgh Drug Discovery Institute, Department of Computational and Systems Biology, Pittsburgh Technology Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Paatero+I%22">Paatero I</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Elenius+K%22">Elenius K</searchLink>; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Laajala+TD%22">Laajala TD</searchLink>; Department of Mathematics and Statistics, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Kurppa+KJ%22">Kurppa KJ</searchLink>; Medicity Research Laboratories, Faculty of Medicine, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Westermarck+J%22">Westermarck J</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland. jukwes@utu.fi.; Institute of Biomedicine, University of Turku, Turku, Finland. jukwes@utu.fi.
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