Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.

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Title: Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
Authors: Pan AL; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Audrain M; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Sakakibara E; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Joshi R; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Zhu X; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Wang Q; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Wang M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Beckmann ND; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Schadt EE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Gandy S; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Zhang B; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Ehrlich ME; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Salton SR; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.; Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Source: Frontiers in aging neuroscience [Front Aging Neurosci] 2024 Jun 28; Vol. 16, pp. 1400447. Date of Electronic Publication: 2024 Jun 28 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101525824 Publication Model: eCollection Cited Medium: Print ISSN: 1663-4365 (Print) Linking ISSN: 16634365 NLM ISO Abbreviation: Front Aging Neurosci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1663-4365
DOI:10.3389/fnagi.2024.1400447